PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.11779/1928

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  • Article
    Citation - Scopus: 1
    High School and University Students' Reasoning About Decision-Making Autonomy and Parental Authority Legitimacy in Child–Mother Conflicts
    (WILEY, 2025-05-02) Kuyel, N.; Acar, M.
    This study investigated youths' reasoning about personal autonomy and maternal authority in hypothetical emerging adult child–mother conflicts in Türkiye. High school and university students (N = 138, Mage = 19.72 years) from secular and religious schools completed a self-report questionnaire including eight conflict scenarios where the mother opposes her child's decision to marry a non-Muslim or get a tattoo. Maternal opposition in hypothetical scenarios was presented in the forms of maternal advice and maternal use of haram opposition. Haram opposition implies the declaration of maternal accrued rights (a concept deeply rooted in Turkish culture) as haram. The results showed that participants were more likely to subordinate child autonomy to maternal authority when the mother in hypothetical scenarios was depicted as using haram opposition. Authoritative parenting appeared to strengthen this effect. This study has shown that haram opposition is a psychological control mechanism to subordinate child autonomy to maternal authority. © 2025 British Psychological Society.
  • Article
    Citation - Scopus: 4
    Economic Impact and Complications of Treated and Untreated Hepatitis C Virus Patients in Turkey
    (Elsevier Inc., 2015-09-01) Altinbaş, Akif; Baser E; Kariburyo, F; Başer, Onur; Baser, Erdem; Kariburyo, M. Furaha
    Background: According to the Turkish Ministry of Health’s guidelines,standard double therapy, a combination of pegylated interferon-alphaand ribavirin, was the only treatment option for patients withhepatitis C virus (HCV) infection until the end of 2011. Objective: Theprimary objective was to compare risk-adjusted clinical and economicoutcomes between treated and untreated patients with HCV infection.Methods: Patients with HCV infection were identified from theTurkish National Health Insurance Database (2009–2011) using International Classification of Diseases, 10th Revision, Clinical Modification codes.The first prescription date was designated as the index date. Mortalityand hepatocellular carcinoma (HCC) rates and health care costs oftreated and untreated patients were compared using propensity scorematching. Baseline demographic and clinical factors were controlledin the models. Subgroup analysis was conducted for patient groupswith and without a cirrhosis diagnosis. Results: Out of 12,990 patientsincluded in the study, 1,583 were treated for HCV infection. Out of2,467 patients who had a cirrhosis diagnosis, 231 were treated,whereas out of 10,523 patients without cirrhosis, 1,352 patients weretreated. Treated patients were younger, less likely to be diagnosedwith comorbid conditions, and less likely to reside in Central orEastern Anatolia. After adjusting for baseline demographic andclinical factors, mortality (2.27% vs. 5.31%; P o 0.001) and HCC rates(0.69% vs. 1.96%; P o 0.001) were found to be lower for treatedpatients. Differences were more significant among patients diagnosedwith cirrhosis. Treated patients incurred higher risk-adjusted annualcosts (€6172 vs. €1680; P o 0.001), mainly because of pharmaceuticalcosts (€4918 vs. €583; P o 0.001). Conclusions: HCV infection treatment, although costly, significantly reduces mortality and HCC ratesin Turkey.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Patterns of International Normalized Ratio Values Among New Warfarin Patients With Nonvalvular Atrial Fibrillation
    (Lippincott Williams & Wilkins, 2016-12-01) Schein, Jeffrey R; Wang, Li; Nelson, Winnie W.; Damaraju, Chandrasekharrao, V; Milentijevic, Dejan; Başer, Onur
    Limited information exists regarding the relationship between international normalized ratio (INR) control/stability and the discontinuation of warfarin therapy among patients with nonvalvular atrial fibrillation (NVAF). This study evaluated the association between INR stabilization and warfarin discontinuation and assessed INR patterns before and after INR stabilization among patients (18 years) with NVAF who newly initiated warfarin (Veterans Health Administration datasets; October 1, 2007 through September 30, 2012). Achievement of INR stabilization (3 consecutive in-range therapeutic INR measurements 7 days apart) was examined from warfarin initiation through the end of warfarin exposure. Proportion of time in therapeutic range during warfarin exposure was calculated (Rosendaal method) and categorized as at least 60% or less than 60%. Among 34346 patients, 49.4% achieved INR stabilization (mean time to stabilization, 98 days). Approximately 40% of INR values were out-of-range, even after achieving stabilization. During 30 days following an INR 4.0 or higher, patients had more INR testing than the overall mean (2.51 vs. 1.67 tests). Warfarin discontinuation was 4.2 times more likely among patients without INR stabilization versus those with INR stabilization (P<0.00001). Patients with poor INR control (time in therapeutic range <60%) were 1.76 times more likely to discontinue warfarin within 1 year (P<0.0001). INR stabilization is a better predictor of warfarin discontinuation than poor INR control. Improved approaches are necessary to maintain appropriate anticoagulation levels among patients with NVAF.
  • Article
    Citation - WoS: 30
    Citation - Scopus: 29
    Out-Of Inr Values and Outcomes Among New Warfarin Patients With Non-Valvular Atrial Fibrillation
    (Springer, 2014-11-27) Schein, Jeffrey R; Wang, Li; Damaraju, Chandrasekharrao, V; Nelson, Winnie W; Başer, Onur
    Background Although efficacious in stroke prevention in non-valvular atrial fibrillation, many warfarin patients are sub-optimally managed. Objective To evaluate the association of international normalized ratio control and clinical outcomes among new warfarin patients with non-valvular atrial fibrillation. Setting Adult non-valvular atrial fibrillation patients (a parts per thousand yen18 years) initiating warfarin treatment were selected from the US Veterans Health Administration dataset between 10/2007 and 9/2012. Method Valid international normalized ratio values were examined from the warfarin initiation date through the earlier of the first clinical outcome, end of warfarin exposure or death. Each patient contributed multiple in-range and out-of-range time periods. Main outcome measure The relative risk ratios of clinical outcomes associated with international normalized ratio control were estimated. Results 34,346 patients were included for analysis. During the warfarin exposure period, the incidence of events per 100 person-years was highest when patients had international normalized ratio < 2:13.66 for acute coronary syndrome; 10.30 for ischemic stroke; 2.93 for transient ischemic attack; 1.81 for systemic embolism; and 4.55 for major bleeding. Poisson regression confirmed that during periods with international normalized ratio < 2, patients were at increased risk of developing acute coronary syndrome (relative risk ratio: 7.9; 95 % confidence interval 6.9-9.1), ischemic stroke (relative risk ratio: 7.6; 95 % confidence interval 6.5-8.9), transient ischemic attack (relative risk ratio: 8.2; 95 % confidence interval 6.1-11.2), systemic embolism (relative risk ratio: 6.3; 95 % confidence interval 4.4-8.9) and major bleeding (relative risk ratio: 2.6; 95 % confidence interval 2.2-3.0). During time periods with international normalized ratio > 3, patients had significantly increased risk of major bleeding (relative risk ratio: 1.5; 95 % confidence interval 1.2-2.0). Conclusion In a Veterans Health Administration non-valvular atrial fibrillation population, exposure to out-of-range international normalized ratio values was associated with significantly increased risk of adverse clinical outcomes.
  • Article
    Citation - WoS: 18
    Citation - Scopus: 23
    Turkish Version of the Multidimensional Measure of Emotional Abuse: Preliminary Psychometrics in College Students
    (Springer, 2018) Hatipoğlu Sümer, Zeynep; Murphy, Christopher M.; Toplu Demirtaş, Ezgi; Sümer, Zeynep Hatipoglu; Demirtas, Ezgi Toplu
    The aim of the current study was to investigate the basic psychometrics of the Multidimensional Measure of Emotional Abuse (MMEA; Murphy & Hoover, 1999) in a Turkish sample. Two hundred and fifty-four college students participated and completed the Turkish version of the MMEA (MMEA-TR) along with the Physical Assault of Conflict Tactics Scale—Revised, Experiences in Close Relationships Inventory, Relationship Assessment Scale, and Social Desirability Questionnaire. Confirmatory factor analysis supported the four-factor structure of the MMEA-TR for both victimization and perpetration reports. This factor structure was cross-validated with an independent older sample of 328 dating college students for perpetration reports. Satisfactory criterion validity and internal consistency reliability results were obtained as well. Based on the preliminary investigation, the MMEA-TR appears to be a psychometrically sound measure of psychological dating aggression perpetration and victimization among college students in Turkey. The results, limitations, and recommendations for future studies were discussed.