PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/20.500.11779/1928
Browse
2 results
Search Results
Article Citation - WoS: 27Citation - Scopus: 30Prevalence of Mastocytosis and Hymenoptera Venom Allergy in the United States(Mosby-Elsevier, 2021-11-01) Volertas, Sofija; Akın, Cem; Khokhar, Dilawar; Schuler, Charles F; Chen, Lu; Yüce, Huseyin; Montejo, Jenny M; Başer, OnurBackground : Mastocytosis is a risk factor for hymenoptera venom anaphylaxis (HVA). Current guidelines recommend measuring tryptase in HVA patients and that those with mastocytosis pursue lifelong venom immunotherapy (VIT). Available data on HVA and mastocytosis largely derives from European single-center studies and the prevalence of HVA with and without mastocytosis in the United States (US) is unknown.Objective : We sought to determine the prevalence of HVA and mastocytosis in the US using an insurance claims database and evaluate the impact of mastocytosis on VIT in HVA patients in a US cohort. Methods :The IBM Watson Database, consisting of insurance claims from approximately 27 million US patients in 2018, was queried to identify patients with HVA and/or mastocytosis. Further, a retrospective study of 161 patients undergoing VIT between 2015 – 2018 at the University of Michigan (U-M) was conducted. Results :In the IBM Watson Database, the prevalence of HVA was 167 per 100,000 (0.167%) and the prevalence of mastocytosis 10 per 100,000 (0.010%) overall and 97 per 100,000 (0.097%) among those with HVA. Mastocytosis showed a 9.7-fold increase among HVA patients versus the general population. In the U-M cohort, 2.6% of VIT patients had mastocytosis. Tryptase level did not correlate with venom reaction severity but was higher in patients with systemic VIT reactions. Conclusions :We observed a lower US HVA prevalence than previously reported. Mastocytosis was more common in US HVA patients, though at lower rates than previously reported. In VIT patients there was no correlation between tryptase level and reaction severity. Key words :Tryptasevenom allergyvenom immunotherapyanaphylaxismastocytosismast cell activation syndromemast cell disease Abbreviations Hymenoptera venom allergyHVAUnited StatesUSVenom immunotherapyVITMast Cell DiseaseMCDAmerican Academy of Allergy, Asthma, and ImmunologyArticle Citation - WoS: 49Citation - Scopus: 55Unraveling the Roles of Distrust, Suspicion of Infidelity, and Jealousy in Cyber Dating Abuse Perpetration: an Attachment Theory Perspective(SAGE Publications, 2020-06-12) Toplu-Demirtaş, Ezgi; Akcabozan-Kayabol, Nazlı Büşra; Araci-Iyiaydin, Ayşegül; Fincham, Frank D.People who are anxiously attached, distrustful and jealous of their partners, and suspect infidelity are more likely to use psychological dating violence. Is this also true for cyber dating abuse perpetration (CDAP)? This study investigated the prevalence of and gender differences in self-reported CDAP and whether trust, anticipated partner infidelity, and jealousy serially mediated the association between anxious attachment and CDAP in a sample of Turkish college students. College students (N = 390) completed the Cyber Dating Violence Inventory, Anxious Attachment subscale of the Experiences in Close Relationship Scale-Short Form, Dyadic Trust Scale, Cognitive Jealousy subscale of the Multidimensional Jealousy Scale, Partners’ Intentions Towards Infidelity Scale, and a Demographic Information Form. A total of 67% of the sample used at least one cyber abusive behavior with their partner over the last 6 months. A multiple serial mediation model indicated that greater anxious attachment was related to more dyadic distrust, the anticipation of partner infidelity, and jealousy, and, in turn, to the use of cyber dating abuse. Overall, results show that the prevalence of CDAP is high and that attachment theory offers a promising framework for identifying predictors of CDAP in emerging adults. These findings have implications for research, intervention, and prevention of CDAP by identifying potential risk factors for perpetrating cyber abuse.