QUBO Formulations and Quantum Optimization for the Multi-Dimensional Knapsack Problem with Conflict, Forcing and Precedence Constraints

Abstract

Constrained knapsack variants are well-suited for QUBO-based quantum optimization, but adding logical relations can inflate the binary model and complicate penalty selection. This work examines the multi-dimensional knapsack problems augmented with conflict, forcing, and precedence (CFP) constraints using Quadratic Unconstrained Binary Optimization (QUBO) models across classical and quantum platforms. The additional logical constraints are incorporated through quadratic penalty terms that modify existing QUBO coefficients without introducing additional binary variables beyond the slack variables used for the capacity constraints. Computational studies are conducted to assess how each of the three constraint types affects solution behavior, including solution quality, computation time, and sensitivity to penalty parameter magnitudes. The approach is demonstrated on representative small-scale instances using QAOA on IBM Quantum gate-based device and quantum annealing on a D-Wave Advantage processor, with results compared with Gurobi as classical solver. The experiments show that the proposed QUBO formulations achieve optimal or near-optimal solutions for small instances, while showing the sensitivity of current quantum hardware to penalty selection, and scaling. Overall, CFP penalties are variable-neutral relative to the slack-based capacity representation, while the capacity terms dominate logical-qubit count and coupling density. Future work may target more compact or hardware-aware capacity modeling.