WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.11779/256

Browse

Now showing 1 - 20 of 721

Citation - WoS: 15
Citation - Scopus: 14
Hepatic Decompensation in Patients With Hiv/Hepatitis B Virus (hbv)/Hepatitis C Virus (hcv) Triple Infection Versus Hiv/Hcv Coinfection and the Effect of Anti-Hbv Nucleos(t)ide Therapy
(2014) Wang, Li; Devine, Scott; Lo Re, Vincent, III; Olufade, Temitope; Başer, Onur
The incidence rate of hepatic decompensation was higher in patients with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) triple infection than in those with HIV/HCV coinfection (24.1 vs 10.8 events per 1000 person-years; hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.12–3.18). Compared with HIV/HCVinfected patients, the rate of decompensation was increased among HIV/HBV/HCV-infected patients receiving no anti-HBV therapy (HR, 2.48; 95% CI, 1.37–4.49) but not among those who did receive such therapy (HR, 1.09; 95% CI, .40–2.97)
Citation - WoS: 1
Citation - Scopus: 2
1441. Quantification of the Flow Noise in Household Refrigerators
(JVE INTERNATIONAL LTD., 2014) Körük, Hasan; Arısoy, Ahmet; Bilgin, Necati
The flow noise in household refrigerators is quantified in this study. First, the sound pressure measurements in a quiet room using typical household refrigerators are conducted and the noise characteristics of the refrigerators are presented. Then, the flow noise in household refrigerators is quantified using the results of the overall analysis and Fourier transform of the measured sound pressure data. After that, the flow noise in household refrigerators is quantified using the sound pressure measurements conducted using a specially designed test rig. The frequency characteristics of the flow noise in household refrigerators are also explored and the contribution of the flow noise is identified.
Citation - WoS: 5
Fuzzy Optimization for Portfolio Selection Based on Embedding Theorem in Fuzzy Normed Linear Spaces
(De Gruyter, 2014) Solatikia, Farnaz; Kılıç, Erdem; Weber, Gerhard-Wilhelm
In this paper, we propose a novel approach Embedding Theoremabout Menger probabilistic normed Spaces. The main idea behind ourapproach consists of taking advantage of interplays between Mengerprobabilistic normed spaces and normed spaces in a way to get anequivalent stochastic program. This helps avoiding pitfalls due to severe over simplification of the reality. The embedding theorem showsthat the set of all fuzzy numbers can be embedded into a Mengerprobabilistic Banach space. Inspired by this embedding theorem, wepropose a solution concept of fuzzy optimization problem which isobtained by applying the embedding function to the original fuzzyoptimization problem.
Citation - WoS: 9
Citation - Scopus: 12
A New Triangular Composite Shell Element With Damping Capability
(Elsevier, 2014) Körük, Hasan; Şanlıtürk, Kenan Yüce
This paper presents a new triangular composite shell element with damping capability. Formulation of the composite triangular shell element is based on stacking individual homogeneous triangular shell ele- ments on top of each other. The homogeneous shell element is an assembly of a triangular membrane element with drilling degrees of freedoms and a plate element. Damping capability is provided by means of complex element stiffness matrix of individual flat layers of the composite element. These elements with damping capability allow modelling general structures with damping treatments. A few test cases are modelled using triangular finite element developed here and the results of the complex eigenvalue analyses are compared with those of the quadrilateral shell elements proposed recently. The results obtained using the presented triangular and previous quadrilateral composite elements are also com- pared with those based on modal strain energy method and experimental results. Comparisons of the experimental and the theoretical results confirm that the modal properties including modal damping lev- els of structures with damping treatments can be predicted with high accuracy using the proposed finite element.
Citation - WoS: 3
Citation - Scopus: 3
Cancer Chemotherapy Treatment Patterns and Febrile Neutropenia in the Us Veterans Health Administration
(2014) Wang, Li; Dale, David C; Barron, Richard; Langeberg, Wendy J; Başer, Onur
Background: The Veterans Health Administration (VHA) is the largest integrated health care system in the United States and a major cancer care provider. Objective: To use VHA database to conduct a population-based study of patterns of myelosuppressive chemotherapy use and to assess the incidence and management of febrile neutropenia (FN) among VHA patients with lung, colorectal, or prostate cancer or non-Hodgkin lymphoma (NHL). Methods: Data were extracted for the initial myelosuppressive chemotherapy course for 27,899 patients who began treatment in the period 2006 to 2011. FN-related costs were defined as claims containing FN diagnosis. Results: Most patients were men (98.0%); most were 65 years or older (55.8%). Patients received a mean 3.4 to 3.9 chemotherapy cycles/course (median cycle duration 34-43 days). The incidence of FN among patients with lung, colorectal, or prostate cancer or NHL was 10.2%, 4.6%, 5.4%, and 17.3%, respectively. Primary or secondary prophylactic antibiotics/colony-stimulating factors were received by 21% and 12% of patients, respectively. Antibiotics were more commonly given as primary or secondary prophylaxis for patients with lung, colorectal, and prostate cancer; colony-stimulating factors were more common for patients with NHL. Among patients with FN, those with lung cancer had the highest inpatient mortality (10%); patients with NHL had the highest costs ($24,571) and the longest hospital length of stay (15.4 days). Conclusions: VHA cancer care was generally consistent with National Comprehensive Cancer Network recommendations; however, compared with the general population, chemotherapy cycles were longer, combination chemotherapy was used less, and treatment to prevent FN was used less, differences that may be attributed to the unique VHA patient population. The impact of these practices warrants further investigation.
Citation - WoS: 12
Citation - Scopus: 17
Quantification and Minimization of Sensor Effects on Modal Parameters of Lightweight Structures
(JVE INTERNATIONAL LTD., 2014) Körük, Hasan
This paper aims to quantify the adverse effects of contact type sensors on modal parameters of lightweight structures and to present a practical way for identification of modal parameters of structures with minimal sensor effects. The adverse effects of a contact type sensor on natural frequencies, damping levels and mode shapes are explored using the theoretical model of a typical beam-like sample carrying a sensor and a controlled experimental study based on measurement of frequency response functions using non-contact excitation and response sensors. The half-power and circle fit modal identification methods are used to extract modal parameter from measured data. The experimental and theoretical modal analysis results are evaluated, and a practical methodology based on classical acoustic and vibration frequency response functions is suggested to identify modal loss factors and natural frequencies of lightweight structures with minimal sensor effects.
Citation - WoS: 54
Citation - Scopus: 64
An Assessment of the Performance of Impedance Tube Method
(Institute of Noise Control Engineering, 2014) Hasan Körük
The impedance tube method is widely used for measuring sound absorption (or reflection) coefficients of acoustic materials as a function of frequency. However, the sound absorption coefficients obtained using the impedance tube method may have some variations due to the dimensions (limits) of an impedance tube, sample preparation and sample mounting. This paper assesses the performance of the two-microphone impedance tube method as a function of frequency for different tube dimensions and materials and presents suggestions for increasing the reliability and repeatability of impedance tube measurements. First, after summarizing a systematic way for measuring acoustic transfer functions, sound absorption coefficients of a variety of materials ranging from conventional absorbing acoustic materials to samples with thin films are measured using two tubes with different tube diameter and microphone spacing. Uncertainty of sound absorption coefficients for various materials is discussed, and the frequency limits of impedance tubes are assessed. Then, a method for minimizing uncertainty due to sample mounting is proposed and the main findings are discussed.
Citation - WoS: 1
Citation - Scopus: 3
The Importance of Rural, Township, and Urban Life in the Interaction Between Social and Emotional Learning and Social Behaviors
(EDAM (Educational Consultancy and Research Center), 2014) Kıyar, Fatma; Totan, Tarık; Atalay, Zümra; Deniz, M. Engin
Whether an individual lives in a rural or urban setting may have direct impact on a wide variety of psychological patterns adopted by students. In this study, the effects of positive and negative social behaviors on the relationship between social and emotional learning needs and skills gaps of students who reside in both rural and urban areas have been examined. The participants of this research consist of 348 female and 319 male students, forming a total of 667 middle school students living in the province of Çanakkale, Turkey as well as in its surrounding areas. The Matson Social Skills Evaluation Scale, the Social-emotional Learning Scale, the Social and Emotional Learning Skills Scale, and personal information form were used to collect data for this research. The Baron and Kenny’s approach and the Sobel test were followed during the examination of the model created in the data analysis process. The mediator test examined the effects of positive and negative social behaviors in relationship to students’ level of social and emotional learning needs and social and emotional learning skills. As a result of this test, it was found that both positive and negative social behaviors exert partial mediation effects over students living in rural and urban areas of the province of Turkey researched.
Citation - WoS: 4
Citation - Scopus: 4
Perceptual Coding-Based Informed Source Separation
(2014) Girin, Laurent; Kırbız, Serap; Ozerov, Alexey; Liutkus, Antoine
Informed Source Separation (ISS) techniques enable manipulation of the source signals that compose an audio mixture, based on a coder-decoder configuration. Provided the source signals are known at the encoder, a low-bitrate side-information is sent to the decoder and permits to achieve efficient source separation. Recent research has focused on a Coding-based ISS framework, which has an advantage to encode the desired audio objects, while exploiting their mixture in an information-theoretic framework. Here, we show how the perceptual quality of the separated sources can be improved by inserting perceptual source coding techniques in this framework, achieving a continuum of optimal bitrate-perceptual distortion trade-offs.
Citation - WoS: 9
Citation - Scopus: 11
A Value-Adding Approach To Reliability Under Preventive Maintenance Costs and Its Applications
(2014) Dubey, Rameshwar; Kılıç, Erdem; Ali, Sadia Samar; Weber, Gerhard Wilhelm
No equipment (system) can be perfectly reliable in spite of the utmost care and best efforts on the part of the designer, decision-maker and manufacturer. The two sides of maintenance are corrective and preventive maintenance. It is generally assumed that a preventive maintenance action is less costly than a repair maintenance action. We examine this proposition in detail on the basis of a failure-time model that relates conformance quality to reliability. Illustratively, we present reliability in the context of contracts with asymmetric information. The model shows how to overcome information rents through price distortions and quantity rationing. The paper ends with a conclusion and an outlook to future studies.
Citation - WoS: 15
Citation - Scopus: 16
An Analysis of Turkey’s Water Diplomacy and Its Evolving Position Vis-À International Water Law
(Taylor & Francis, 2014) Kibaroğlu, Ayşegül
This article analyzes Turkey’s transboundary water policy by examining its institutional framework and basic principles. It explores the reasons why Turkey voted against the UN Watercourses Convention. Turkey’s harmonization with the water law of the European Union is also scrutinized with an aim to assess its implications for transboundary water policy making. Turkish water diplomacy faces new challenges, such as the devastating impacts of prolonged droughts as well as ongoing instability and conflicts in Syria and Iraq. Hence, it is imperative for Turkey to systematically reconcile its water policy objectives in accordance with the global norms that are adopted in this field
Citation - WoS: 1
Pnd29 - a Retrospective Analysis of the Economic Burden Among Patients Diagnosed With Chronic Migraine Using the Veterans Health Administration Medical Data
(2015) Mao, X; Shrestha, S; Başer, Onur; Wang, L
OBJECTIVES: To evaluate the health care resource utilization and costsamong patients diagnosed with chronic migraine (CM) in the Veterans HealthAdministration (VHA) medical dataset. METHODS: Patients diagnosed with CMwere identified (International Classification of Diseases, 9th Revision, ClinicalModification diagnosis code 346.XX) using the VHA dataset from October 1, 2008through September 30, 2010. The initial diagnosis date was designated as the indexdate. Patients without CM with the same age, gender and region (comparison cohort)were matched using a randomly chosen index date to minimize selection bias.Patients in both cohorts were at least age 18 years and had continuous medicaland pharmacy benefits for 1 year before and after the index date. One-to-one propensity score matching (PSM) was used to compare health care costs and utilizations between the CM and the comparison cohorts, and was adjusted for baselinedemographic and clinical characteristics. Pain scores were also included to investigate wellness after CM diagnosis. RESULTS: After risk-adjustment by PSM, 123,241patients in each cohort were matched. Significantly more CM patients had inpatientadmissions (6.44% vs. 1.75%, p<0.0001) and emergency room (ER; 14.42% vs. 5.50%,p<0.0001), outpatient office (68.80% vs. 42.15%, p<0.0001), outpatient (69.30% vs.42.91%, p<0.0001) and pharmacy visits (70.84% vs. 41.43%, p<0.0001) compared tothose without CM. Accordingly, CM patients also incurred higher costs for inpatient admissions and ER, office, outpatient and pharmacy visits compared to thosewithout CM. Total costs incurred by CM patients were $4,776, almost triple that of patients without CM ($1,756). There were more CM patients with accompanying painat all levels (mild: 19.53% vs. 0.16%; moderate: 13.10% vs. 0.10%; severe: 16.20% vs.0.12%; all p<0.0001). CONCLUSIONS: CM patients in the VHA population had substantial health care resource utilization, incurred higher costs and suffered worsepain compared to those without the disease.
Prs23 - a Descriptive Analysis of Patient Characteristics and Health Care Burden Associated With Chronic Obstructive Pulmonary Disease in the Us Medicare Population
(2015) Xie, L.; Kariburyo, M. Furaha; Wang, Y; Başer, Onur
Objectives: To evaluate the patient characteristics and health care burden associated with chronic obstructive pulmonary disease (COPD) in the U.S. Medicarepopulation. Methods: COPD patients were identified (International Classificationof Disease, 9th Revision, Clinical Modification [ICD-9-CM] codes: 491.xx, 492.xx and496.xx) using U.S. national Medicare claims from 01JAN2007 to 31DEC2010. The firstdiagnosis date was designated as the index date. Patients were required to: a) be age?65 years on the index date; b) have continuous medical and pharmacy benefits for 12months pre-index date (baseline period); c) have continuous enrollment for 12 monthspost-index date (follow-up period), unless there was earlier evidence of death; and d)have no COPD diagnosis pre-index date. The outcomes of interest included medicationuse, including a long-acting beta agonist (LABA) or LABA/inhaled corticosteroid (ICS)combination, mortality and health care resource utilization and costs. Results: Atotal of 543,249 COPD patients were identified. Patients were, on average, age 78 years.Most patients were white (94%) and resided in the South U.S. region (41%). The averageCharlson Comorbidity Index score was 3.23, and hypertension (67%), diabetes (28%),congestive heart failure (21%) and chronic pulmonary disease (20%) were the mostfrequently diagnosed comorbidities. A 13.82% mortality rate was observed duringthe first year of the follow-up period. Post-index LABA medications, including arfomoterol (0.55%), formoterol (0.25%) and salmeterol (0.32%) were prescribed to 1.10%of the population. Identified LABA/ICS combinations included budesonide/formoterol(1.97%) and fluticasone/salmeterol (10.02%). High health care resource utilization wasencountered for Medicare carrier (99.40%), pharmacy (90.27%), outpatient (76.52%)and inpatient visits (48.83%). The main cost drivers were inpatient ($10,645), Medicarecarrier ($4,888), outpatient ($3,322) and skilled nursing facility ($2,695) costs, resultingin $25,397 in total health care costs. Conclusions: U.S. Medicare patients have ahigh COPD-related health care burden
Pih13 - Examining the Fracture-Related Cost Burden and Health Care Resource Utilization Post-Menopause in the Us Medicare Population
(2015) Xie, L; Keshishian, A; Du, J; Başer, Onur
Objectives: To examine the fracture-related cost burden and healthcareresource utilization among post-menopausal women in the U.S. Medicare population. Methods: Post-menopausal women were identified using InternationalClassification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosiscodes from the U.S. Medicare claims dataset from 01JAN2008 through 31DEC2012.The first fracture diagnosis date was designated as the index date. One year ofcontinuous health plan enrollment was required for all patients pre- and postindex date. A comparison group was created, identifying patients without fracturesof the same age, region, gender and index year and were matched to case patientsbased on baseline Charlson Comorbidity Index scores. A randomly chosen indexdate for the comparison group reduced selection bias. Healthcare costs and utilizations were compared using 1:1 propensity score matching (PSM). Results: Beforematching (n=182,124), patients with fractures were more likely to be white (92.6%vs. 85.8%), reside in the Northeast U.S. region (19.4% vs. 16.4%), and have diagnosis of depression (18.0% vs. 13.0%) and chronic obstructive pulmonary disease(26.3% vs. 23.3%). After 1:1 PSM, 65,549 patients were included in each cohort andbaseline characteristics were well-balanced. Significantly more post-menopausalwomen with fractures had inpatient admission (42.3% vs. 8.6%, p<0.0001), outpatient (80.3% vs. 48.7%, p<0.0001), home health agency (31.2% vs. 6.9%, p<0.0001)skilled nursing facility (SNF) (25.7% vs. 2.72%, p<0.0001) and hospice admission(1.4% vs. 1.0%, p<0.0001) claims. Higher healthcare resource utilization translated to higher costs for post-menopausal fracture patients, including inpatient($7,869 vs. $1,203, p<0.0001), outpatient ($1,928 vs. $622, p<0.0001), SNF ($5,980vs. $437, p<0.0001), hospice ($338 vs. $244, p<0.0001), pharmacy ($1,052 vs. $829,p<0.0001) and total costs ($23,097 vs. $5,247, p<0.0001), than for those in the comparison cohort. Conclusions: Post-menopausal women with fractures in theU.S. Medicare population had higher healthcare resource utilization and expenditures than those without fractures.
Demographic Distribution and Health Care Burden of Patients Diagnosed With Ankylosing Spondylitis in the Us Medicare Population
(2015) Mao, X; Li, L; Shrestha, S; Başer, Onur; Yuce, H; Wang, L
OBJECTIVES: To investigate the demographic distribution and health care burdenof patients diagnosed with ankylosing spondylitis (AS) using Medicare fee-forservice (FFS) data. METHODS: A retrospective analysis was performed using the100% Medicare FFS Datasets from October 1, 2008 through December 31, 2012.Patients diagnosed with AS were identified using International Classification ofDiseases, 9th Revision, Clinical Modification diagnosis code 720.0, and the firstdiagnosis date was designated as the index date. All patients were required tohave continuous medical and pharmacy benefits 1-year pre- (baseline period)and post-index date (follow-up period). Health care resource utilization and costsduring the baseline and follow-up periods were calculated. RESULTS: A total of8,990 AS patients were included in the study. The average age at diagnosis was 75years. Nearly 88.7% of patients were white, 62.97% were women and many residedin the South U.S. region (40.33%). The most common baseline comorbidities werechronic obstructive pulmonary disease (33.20%), diabetes (30.50%), cerebrovasculardisease (22.65%) and congestive heart failure (18.85%). During the follow-up period,73.04% of patients had inpatient admissions, 52.31% had emergency room visits,91.43% had outpatient office visits, 91.43% had outpatient visits and 57.67% hadpharmacy visits, resulting in average costs of, $37,077, $298, $5,397, $5,695 and$6,668, respectively. The average total costs were $49,440 during the follow-upperiod. The four most frequently prescribed medications for AS were prednisonehydrocodone (3.59%), bit/acetaminophen (3.17%), methotrexate sodium (2.79%)and levothyroxine sodium (2.42%). CONCLUSIONS: AS patient demographic andclinical characteristics in the Medicare population were assessed. Study patientswere often diagnosed with comorbid conditions, and had high health care utilization and costs.
Psy14 - Evaluating Trends in Chronic Pain Prevalence in the United States Veterans Health Administration Population
(2015) Li, L.; Shrestha, S.; Başer, Onur; Yuce, H; Wang, L
OBJECTIVES: The current study examined chronic pain prevalence in the U.S. Veterans Health Administration (VHA) population. METHODS: The study sample was based on the VHA Medical SAS Datasets from fiscal year 2008 through 2012. All patients diagnosed with chronic pain throughout the study period were identified using International Classification of Diseases, 9th Revision, Clinical Modification diagnosis codes 338.2 and 338.4. The variation in the prevalence of chronic pain was assessed and categorized according to the pain scale. Pain score was determined using a scale ranging from 0 to 10 as reported by patients using the following categories: 1 to 4: mild, 5 to 6: moderate and ?7: severe pain. To identify prior prevalence cases, we restricted continuous enrollment throughout that fiscal year and at least 2 years prior
Pcn62 - Assessing the Economic Burden and Health Care Resource Utilizations of Us Medica Re Patients With Myeloproliferative Neoplasms
(2015) Keshishian, A; Du, J; Xie, L; Başer, Onur
OBJECTIVES: To examine the economic burden and health care resource utilization of myeloproliferative neoplasms (MPNs) in the U.S. Medicare population. METHODS: A retrospective data analysis was performed using the U.S.national Medicare claims from January 2008 through December 2012. MPN patientswere identified using International Classification of Disease 9th Revision ClinicalModification (ICD-9-CM) diagnosis codes 238.4, 238.71, 238.76 and 289.83. The diagnosis date was designated as the index date. A comparison cohort without a MPNdiagnosis was created for patients of the same age, region, gender, index year andbaseline Charlson Comorbidity Index score. A random index date was chosen forthe comparison cohort to reduce selection bias. Patients were required to havecontinuous medical and pharmacy benefits 1 year pre- and post-index date. Oneto-one propensity score matching (PSM) was performed to compare follow-uphealth care costs and utilizations between the cohorts, adjusting for demographicand clinical characteristics. RESULTS: Eligible patients (N=17,950) were identifiedfor the MPN and comparison cohorts. After 1:1 PSM, a total of 5,546 patients werematched from each cohort and baseline characteristics were well-balanced. MPNpatients had a higher percentage of health care resource utilizations, includingMedicare carrier (98.6% vs. 65.9%), Durable Medical Equipment (DME; 29.5% vs.14.4%), Home Health Agency (HHA; 12.4% vs. 5.0%), outpatient visits (76.6% vs.37.4%), inpatient hospitalizations (27.2% vs. 6.8%) and Skilled Nursing Facility (SNF;7.5% vs. 2.0%) visits than non-MPN patients. Patients diagnosed with MPNs alsoincurred significantly higher costs, including Medicare carrier ($3,872 vs. $1,283),DME ($266 vs. $91), HHA ($639 vs. $250), outpatient ($10,061 vs. $3,204), inpatient($5,449 vs. $1,054), pharmacy ($1,069 vs. $713) and total health care costs ($23,060vs. $7,076; p<0.0001). CONCLUSIONS: MPN patients had a higher burden of illnesscompared to non-MPN patients.
Citation - Scopus: 1
Biology, Real Time and Multimodal Design Cell-Signaling as a Realtime Principle in Multimodal Design
(2015) Teixeira, Frederico Fialho
The common understanding of morphogenesis implies a three-dimensional evolutionary change in form witnessed in the developmental process of an organism. This evolutionary process emerges from cell growth, cellular differentiation and environmental changes that generate specific conditions between genotype and phenotype. The complex nature of these aspects is intrinsic to evolutionary biology, and its accurate implementation in bio-generated architectures potentiates a twofold understanding of different morphogenetic strategies and its spatial consequences. Within this premise the morphogenetic factors of cell-differentiation and cell-signaling become a crucial aspect in a real-time communication system between an archetype and space, thus performing within particular modes in which design correlates to space. The paper hypothesizes and tests the use of Cell-Signaling as system of communication that governs fundamental cellular activities within the process of Gastrulation. This process occurs in early cell-embryo development and where communication between cells is favorably active and cellular the structure is established. The Emosphera project is a technical re-contextualization of this specific morphogenetic process. The principles denote a genetic code of the object can be scripted in a CAD environment and reproduced real-time by means of communication through a multimedia platform, which render form as a consequential aspect.
Citation - Scopus: 2
Strong Transient Effects of the Flow Around a Harmonically Plunging Naca0012 Airfoil at Low Reynolds Numbers
(Springer, 2015) Yücel, S. Banu; Şahin, Mehmet; Ünal, M. Fevzi
Abstract The flow pattern around a NACA0012 airfoil undergoing harmonic plunging motion corresponding to the deflected wake phenomenon reported by Jones and Platzer (Exp Fluids 46:799–810, 2009) is investigated in detail using direct numerical simulations. An arbitrary Lagrangian–Eulerian formulation based on an unstructured side-centered finite volume method is utilized in order to solve the incompressible unsteady Navier–Stokes equations. The Reynolds number is chosen to be 252, and the reduced frequency of plunging motion (k = 2?fc/U?) and the plunge amplitude non-dimensionalized with respect to chord are set to be 12.3 and 0.12, respectively, as in the experimental study of Jones and Platzer (2009). The present numerical simulations reveal a highly persistent transient effect, and it takes two orders of magnitude larger duration than the heave period to reach the time-periodic state. In addition, the three-dimensional simulation reveals that the flow field is three-dimensional for the parameters used herein. The calculation reproduces the deflected wake and shows a good agreement with the experimental wake pattern. The instantaneous vorticity contours, finite-time Lyapunov exponent fields and particle traces are presented along with the aerodynamic parameters including the lift and thrust coefficients.
Pms37 - Health Care Cost Burden and Demographic Distribution of Patients Diagnosed With Psoriatic Arthritis in the Us Medicare Population
(2015) Li, L; Mao, X; Shrestha, S; Başer, Onur; Yuce H.; Li Wang
OBJECTIVES: To investigate the health care cost burden and demographic distributionof patients diagnosed with psoriatic arthritis (PSA) in the Medicare fee-for-service(FFS) Dataset. METHODS: A retrospective database analysis was performed usingthe 100% Medicare FFS Datasets from October 1, 2008 through December 31, 2012.Patients diagnosed with PSA were identified using International Classification ofDiseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis code 696.0, andthe index date was the date of the initial diagnosis. All patients were required to havecontinuous medical and pharmacy benefits 1-year pre- and post-index date. Healthcare costs and utilization during the baseline (1 year before the diagnosis date) andfollow-up (1 year after the diagnosis date) periods were calculated. RESULTS: Usingthe aforementioned criteria, 11,324 PSA patients were identified. The average ageat diagnosis was 74 years, 66.10% of patients were women and almost 92.36% werewhite. The majority of patients resided in the South U.S. region (39.01%). Diabetes(33.84%), chronic obstructive pulmonary disease (29.04%) and cerebrovascular disease(17.36%) were the main comorbidities observed during the baseline period. Duringthe follow-up period, 62.96% of patients had inpatient admissions, 47.29% had emergency room visits, 91.67% had outpatient office visits, 91.67% had outpatient visitsand 58.03% had pharmacy visits, costing, on average, $23,960, $237, $5,015, $5,252and $7,335, respectively. The average total cost of PSA patients was $36,548. The fivemost commonly prescribed medications for PSA were methotrexate sodium (4.54%),prednisone (3.37%), levothyroxine sodium (2.59%), hydrocodone bit/acetaminophen(2.43%) and simvastatin (2.11%). CONCLUSIONS: PSA patient demographic and healthcare cost information was obtained and the most commonly prescribed PSA medications were identified.

Browse

Browsing WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection by Issue Date