PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
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Article A Preliminary Study on the Role of Personal History of Infectious and Parasitic Diseases on Self-Reported Health Across Countries(W B Saunders Co Ltd, 2025) Pfuhl, Gerit; Prazeres, Filipe; Kowal, Marta; Aavik, Toivo; Abad-Villaverde, Beatriz; Afhami, Reza; Sorokowski, Piotr; Toplu-Demirtaş, EzgiObjectives: Infectious diseases are often associated with decline in quality of life. The aim of this study is to analyze the relationship between personal history of communicable, i.e., infectious and parasitic diseases and self-rated health. Study design: Secondary analysis of a large dataset multi-country observational study. Methods: We used a four-pronged analysis approach to investigate whether personal history of infectious and parasitic diseases is related to self-reported health, measured with a single item. Results: Three of the four analyses found a small positive effect on self-reported health among those reporting a history of pathogen exposure. The meta-analysis found no support but large heterogeneity that was not reduced by two classifications of countries. Conclusion: Personal history of infectious and parasitic diseases does not reduce self-reported health across a global sample.Article Citation - WoS: 23Citation - Scopus: 25Acoustic Particle Palpation for Measuring Tissue Elasticity(American Institute of Physics, 2015) El Ghamrawy, Ahmed; Körük, Hasan; Choi, James J; Pouliopoulos, Antonios NWe propose acoustic particle palpation—the use of sound to press a population of acoustic particles against an interface—as a method for measuring the qualitative and quantitative mechanical properties of materials. We tested the feasibility of this method by emitting ultrasound pulses across a tunnel of an elastic material filled with microbubbles. Ultrasound stimulated the microbubble cloud to move in the direction of wave propagation, press against the distal surface, and cause deformations relevant for elasticity measurements. Shear waves propagated away from the palpation site with a velocity that was used to estimate the material’s Young’s modulus.Article Citation - WoS: 4Citation - Scopus: 6An Online Laboratory School Research on Pre-Service Mathematics Teachers’ Experiences and Mathematics Teaching Anxiety(Springer, 2022) Ölmez, İbrahim Burak; Taylan, Rukiye Didem; Pekkan, Tunç ZelhaDuring the COVID-19 pandemic, we founded an Online Laboratory School (OLS) under the roof of a university in Turkey to support students from public schools that were not technologically prepared for an online education and to provide an opportunity for our pre-service teachers (PSTs) to continue their internship by teaching online. The purpose of this research, consisting of two studies, was to examine experiences of 43 PSTs (first-, third- and fourth-years) during the OLS period of 8 weeks and how the OLS affected their mathematics teaching anxiety during Fall 2020. In the first study, we administered a survey to inquire into PSTs’ views on their experiences at the OLS, and in the second study we examined their mathematics teaching anxiety before and after the OLS experience using another survey. One main result was that the OLS experience served as an effective introduction to the profession for first-year PSTs and fourth- and third-year PSTs reported learning in-depth about online teaching in terms of the planning, teaching, and reflecting cycle. Another main result was that PSTs had mathematics teaching anxiety from “a little” to “a moderate amount” before the OLS and their teaching anxiety did not significantly change during the OLS period of 8 weeks. PSTs experienced highest mathematics teaching anxiety when they were observed and evaluated by supervisors during their teaching. The implications of these findings are discussed for teacher education programs.Article Citation - WoS: 46Citation - Scopus: 53An Optimization Model for Carbon Capture & Storage/Utilization Vs. Carbon Trading: a Case Study of Fossil-Fired Power Plants in Turkey(2018) Uctug, Fehmi Görkem; Ağralı, Semra; Türkmen, Burçin AtılganWe consider fossil-fired power plants that operate in an environment where a cap and trade system is in operation. These plants need to choose between carbon capture and storage (CCS), carbon capture and utilization (CCU), or carbon trading in order to obey emissions limits enforced by the government. We develop a mixed-integer programming model that decides on the capacities of carbon capture units, if it is optimal to install them, the transportation network that needs to be built for transporting the carbon captured, and the locations of storage sites, if they are decided to be built. Main restrictions on the system are the minimum and maximum capacities of the different parts of the pipeline network, the amount of carbon that can be sold to companies for utilization, and the capacities on the storage sites. Under these restrictions, the model aims to minimize the net present value of the sum of the costs associated with installation and operation of the carbon capture unit and the transportation of carbon, the storage cost in case of CCS, the cost (or revenue) that results from the emissions trading system, and finally the negative revenue of selling the carbon to other entities for utilization. We implement the model on General Algebraic Modeling System (GAMS) by using data associated with two coal-fired power plants located in different regions of Turkey. We choose enhanced oil recovery (EOR) as the process in which carbon would be utilized. The results show that CCU is preferable to CCS as long as there is sufficient demand in the EOR market. The distance between the location of emission and location of utilization/storage, and the capacity limits on the pipes are an important factor in deciding between carbon capture and carbon trading. At carbon prices over $15/ton, carbon capture becomes preferable to carbon trading. These results show that as far as Turkey is concerned, CCU should be prioritized as a means of reducing nationwide carbon emissions in an environmentally and economically rewarding manner. The model developed in this study is generic, and it can be applied to any industry at any location, as long as the required inputs are available. (C) 2018 Elsevier Ltd. All rights reserved.Article Citation - WoS: 17Citation - Scopus: 23Benefit of Early Discharge Among Patients With Low-Risk Pulmonary Embolism(2017) Wang, Li; Wells, Phil; Fermann, Gregory J; Peacock, W. Frank; Schein, Jeff; Coleman, Craig I; Crivera, Concetta; Başer, OnurClinical guidelines recommend early discharge of patients with low-risk pulmonary embolism (LRPE). This study measured the overall impact of early discharge of LRPE patients on clinical outcomes and costs in the Veterans Health Administration population. Adult patients with >= 1 inpatient diagnosis for pulmonary embolism (PE) (index date) between 10/2011-06/2015, continuous enrollment for >= 12 months pre-and 3 months post-index date were included. PE risk stratification was performed using the simplified Pulmonary Embolism Stratification Index. Propensity score matching (PSM) was used to compare 90-day adverse PE events (APEs) [recurrent venous thromboembolism, major bleed and death], hospital-acquired complications (HACs), healthcare utilization, and costs among short (<= 2 days) versus long length of stay (LOS). Net clinical benefit was defined as 1 minus the combined rate of APE and HAC. Among 6,746 PE patients, 95.4% were men, 22.0% were African American, and 1,918 had LRPE. Among LRPE patients, only 688 had a short LOS. After 1:1 PSM, there were no differences in APE, but short LOS had fewer HAC (1.5% vs 13.3%, 95% CI: 3.77-19.94) and bacterial pneumonias (5.9% vs 11.7%, 95% CI: 1.24-3.23), resulting in better net clinical benefit (86.9% vs 78.3%, 95% CI: 0.84-0.96). Among long LOS patients, HACs (52) exceeded APEs (14 recurrent DVT, 5 bleeds). Short LOS incurred lower inpatient ($2,164 vs $5,100, 95% CI: $646.8-$5225.0) and total costs ($9,056 vs $12,544, 95% CI: $636.6-$6337.7). LRPE patients with short LOS had better net clinical outcomes at lower costs than matched LRPE patients with long LOS.Article Big-5 Personality Traits as Predictors of Allostatic Load in Latino Americans: A Longitudinal Study(Oxford Univ Press Inc, 2025) Sevi, Baris; Supiyev, Adil; Gutierrez, Angela; Graham, Eileen K.; Mroczek, Daniel K.; Muniz-Terrera, GracielaObjectives Allostatic load (AL) refers to the measure of cumulative wear and tear resulting from chronic stress and life events. AL presents adverse consequences for a diverse range of health conditions, and Latino populations show a high risk for elevated AL. This study aimed to test the Big-5 personality traits as possible predictors of AL in Latinos.Methods Using data from the Health and Retirement Study, we examined the Big-5 and AL connection through three time points in 8 years (Time 1 = 2006/2008; Time 2 = 2010/2012; Time 3 = 2014/2016). Only self-identified Latinos were included in the analysis sample (N = 319). Big-5 and demographics were obtained at baseline, and AL scores were computed for each time point.Results First, separate longitudinal linear mixed-effect models examined the effects of each Big-5 personality trait on AL change over time, then a fully adjusted longitudinal linear mixed-effect model was tested entering the Big-5 personality traits simultaneously. All models controlled for sociodemographic factors. Conscientiousness emerged as the only consistent significant predictor, for the separate and the simultaneous models. In baseline associations, higher conscientiousness was associated with lower AL. For predicting change in AL over time, none of the personality traits had significant associations in any of the models.Discussion The findings bolster prior evidence that conscientious can be a protective factor against elevated AL. Conscientiousness is a possible protective factor and improving related traits can be a path to achieve better health in Latino Americans.Article Body Appreciation Matters: The Associations Between Self-Compassion, Body Appreciation, and Disordered Eating Behaviors Among Heterosexual and LGBi Plus Emerging Adults in Türkiye(Sage Publications inc, 2025) Deveci, Ayse Nur; Demirtas, Ezgi Toplu; Bulgan, GokceObjectives: Self-compassion has been effective in the prevention and treatment of disordered eating behaviors and body image issues, which are significant public health concerns with potential psychosocial and physical consequences. Furthermore, there remains a substantial gap in the existing body of research, particularly in the context of heterosexual, lesbian, gay, and bisexual plus (LGBi+) emerging adults in T & uuml;rkiye. Therefore, this study aims to explore the mediating role of body appreciation in the relationship between self-compassion and disordered eating behaviors and the moderating role of sexual orientation (heterosexual and LGBi+) in the mediation among emerging adults. Methods: A diverse sample of participants comprising heterosexual (n = 242) and LGBi+ (n = 204) emerging adults (Mage = 22.18; SDage = 3.07; min = 18; max = 30) completed self-report measures of the Self-Compassion Scale, Body Appreciation Scale-2, and Eating Attitude Test-26. Results: The results of moderated meditation revealed that body appreciation mediated the relationship between self-compassion and disordered eating behaviors among both heterosexual and LGBi+ individuals. Conclusions: The findings may inform support strategies and interventions to reduce eating disorder risk and promote mental health and well-being in both heterosexual and LGBi+ populations by emphasizing self-compassion and body appreciation.Article Citation - WoS: 3Citation - Scopus: 3Cancer Chemotherapy Treatment Patterns and Febrile Neutropenia in the Us Veterans Health Administration(2014) Wang, Li; Dale, David C; Barron, Richard; Langeberg, Wendy J; Başer, OnurBackground: The Veterans Health Administration (VHA) is the largest integrated health care system in the United States and a major cancer care provider. Objective: To use VHA database to conduct a population-based study of patterns of myelosuppressive chemotherapy use and to assess the incidence and management of febrile neutropenia (FN) among VHA patients with lung, colorectal, or prostate cancer or non-Hodgkin lymphoma (NHL). Methods: Data were extracted for the initial myelosuppressive chemotherapy course for 27,899 patients who began treatment in the period 2006 to 2011. FN-related costs were defined as claims containing FN diagnosis. Results: Most patients were men (98.0%); most were 65 years or older (55.8%). Patients received a mean 3.4 to 3.9 chemotherapy cycles/course (median cycle duration 34-43 days). The incidence of FN among patients with lung, colorectal, or prostate cancer or NHL was 10.2%, 4.6%, 5.4%, and 17.3%, respectively. Primary or secondary prophylactic antibiotics/colony-stimulating factors were received by 21% and 12% of patients, respectively. Antibiotics were more commonly given as primary or secondary prophylaxis for patients with lung, colorectal, and prostate cancer; colony-stimulating factors were more common for patients with NHL. Among patients with FN, those with lung cancer had the highest inpatient mortality (10%); patients with NHL had the highest costs ($24,571) and the longest hospital length of stay (15.4 days). Conclusions: VHA cancer care was generally consistent with National Comprehensive Cancer Network recommendations; however, compared with the general population, chemotherapy cycles were longer, combination chemotherapy was used less, and treatment to prevent FN was used less, differences that may be attributed to the unique VHA patient population. The impact of these practices warrants further investigation.Article Citation - WoS: 21Citation - Scopus: 22Correction To: Validation of the Short Version (tls-15) of the Triangular Love Scale (tls-45) Across 37 Language(Springer, 2023) Dinić, Bojana M.; Sorokowski, Piotr; Toplu Demirtaş, Ezgi; Frederick, David A.; Pisanski, Katarzyna; Kowal, Marta; Gjoneska, BiljanaLove is a phenomenon that occurs across the world and affects many aspects of human life, including the choice of, and process of bonding with, a romantic partner. Thus, developing a reliable and valid measure of love experiences is crucial. One of the most popular tools to quantify love is Sternberg’s 45-item Triangular Love Scale (TLS-45), which measures three love components: intimacy, passion, and commitment. However, our literature review reveals that most studies (64%) use a broad variety of shortened versions of the TLS-45. Here, aiming to achieve scientific consensus and improve the reliability, comparability, and generalizability of results across studies, we developed a short version of the scale—the TLS-15—comprised of 15 items with 5-point, rather than 9-point, response scales. In Study 1 (N = 7,332), we re-analyzed secondary data from a large-scale multinational study that validated the original TLS-45 to establish whether the scale could be truncated. In Study 2 (N = 307), we provided evidence for the three-factor structure of the TLS-15 and its reliability. Study 3 (N = 413) confirmed convergent validity and test–retest stability of the TLS-15. Study 4 (N = 60,311) presented a large-scale validation across 37 linguistic versions of the TLS-15 on a cross-cultural sample spanning every continent of the globe. The overall results provide support for the reliability, validity, and cross-cultural invariance of the TLS-15, which can be used as a measure of love components—either separately or jointly as a three-factor measure.Article Cross-Cultural Data on Romantic Love and Mate Preferences From 117,293 Participants Across 175 Countries(Nature Research, 2025) Kowal, Marta; Sorokowski, Piotr; Gjoneska, Biljana; Pisanski, Katarzyna; Pfuhl, Gerit; Aguilar, Leonardo; Prazeres, Filipe; Toplu-Demirtaş, EzgiPsychological studies on close relationships have often overlooked cultural diversity, dynamic processes, and potentially universal principles that shape intimate partnerships. To address the limited generalizability of previous research and advance our understanding of romantic love experiences, mate preferences, and physical attractiveness, we conducted a large-scale cross-cultural survey study on these topics. A total of 404 researchers collected data in 45 languages from April to August 2021, involving 117,293 participants from 175 countries. Aside from standard demographic questions, the survey included valuable information on variables relevant to romantic relationships: intimate, passionate, and committed love within romantic relationships, physical-attractiveness enhancing behaviors, gender equality endorsement, collectivistic attitudes, personal history of pathogenic diseases, relationship quality, jealousy, personal involvement in sexual and/or emotional infidelity, relational mobility, mate preferences, and acceptance of sugar relationships. The resulting dataset provides a rich resource for investigating patterns within, and associations across, a broad range of variables relevant to romantic relationships, with extensive opportunities to analyze individual experiences worldwide. © The Author(s) 2025.Article Citation - WoS: 13Citation - Scopus: 18Crossing Boundaries: a Pilot Study of Maternal Attitudes About Child Maltreatment in Nine Countries(Elsevier, 2020) Emmen, R; Soares, I; Wang, L; Alink, L; Mesman, J; Mels, C; Asanjarani, F.; Carcamo, R; Hsiao, C; Selcuk, B; Branger, M.a, Woudstra, M.-L; Yavuz, Melis; Van Ginkel, JBackground: Definitions of child maltreatment vary widely between studies, and even more so between different cultural contexts. Objective: In this pilot study, we examine between-country variations in maternal notions about what constitutes child maltreatment. Participants and setting: The sample consisted of 466 mothers recruited in Chile, China, Greece, Iran, the Netherlands, Portugal, South Africa, Turkey, and Uruguay. Methods: All mothers completed a new Q-sort measure, ranking 90 parenting behaviors linked to subtypes of maltreatment (emotional neglect, emotional abuse, physical neglect, and physical abuse) from least to most detrimental to child development. Results: Between-country agreement regarding the harmfulness of the parenting behaviors was high (r =.45), but there were different patterns of reported harmfulness of subtypes of maltreatment (although driven mostly by deviating patterns in the South African sample). Further, there were significant country effects on the number and type of behaviors labeled as maltreatment (p?2 =.15), and the number of items labeled as requiring intervention (p?2 =.19). Conclusions: Variations in conceptions of maltreatment need to be studied in larger more representative samples and taken into account in the assessment and treatment of child maltreatment across cultures.Article Citation - WoS: 19Citation - Scopus: 20Culturally Shared and Unique Meanings and Expressions of Maternal Control Across Four Cultures(American Psychological Association, 2021) Selçuk, Bilge; Cheah, Charissa S L; Şen, Hilal H.; Park, Seong-Yeon; Vu, Kathy T T; Cho, Hyun Su; Yavuz, H MelisMaternal control is a major dimension of parenting and has different meanings, practices, and potential consequences across cultures. The present study aimed to identify and compare mothers' conceptualizations of parenting control across four cultures to reveal a more nuanced understanding regarding the meaning and practices of control: European American, Chinese immigrant, Korean immigrant, and Turkish. Using a semistructured open-ended interview, 100 European American, 102 U.S. Chinese immigrant, 103 U.S. Korean immigrant, and 109 Turkish mothers of preschool-aged children reported the ratings of importance, specific reasons, and strategies for exerting control over their children in daily life. Results revealed both shared and unique conceptualizations of maternal control across four cultures. Specifically, all mothers reported that it is important to express maternal control over their children in order to set behavioral norms/standards, maintain child safety, support social relations and respect for others, provide guidance, and guide moral development. Moreover, mothers discussed utilizing nonphysical punishment, setting and maintaining rules, reasoning/negotiating, consistency, physical punishment and verbal control, showing parents' serious/stern attitude, correction, and psychological control forms of control. However, the levels at which mothers emphasize the different reasons and strategies varied across cultures, reflecting culturally emphasized values. The findings of the present study further enrich our understanding of the complexities of maternal control across cultures. (PsycInfo Database RecordArticle Citation - WoS: 2Citation - Scopus: 1Cyber Dating Violence Among Youth and Adolescents: a Systematic Review and Meta-Analysis(Springer/plenum Publishers, 2024) Erbiçer, Eyüp Sabır; Boranlı, Ece Nur; Metin, Ahmet; Erbiçer, Sinem; Şen, Sedat; Toplu Demirtaş, Ezgi; Espelage, Dorothy L.Studies have shown that there are protective and risk factors related to cyber dating violence. However, the effect size of these factors is unclear. This study aims to clarify the effect size of the associations of protective and risk factors, as well as symptoms of mental health conditions, with cyber dating violence perpetration and victimization. Databases, including PubMed, Web of Science (WoS), ProQuest, Scopus, and EBSCOhost were searched to identify relevant studies. Forty-nine studies were included in the current study. Results revealed statistically significant and medium relationships between cyber dating violence perpetration and some risk factors, including offline dating violence perpetration-related factors (i.e., physical, psychological, sexual, relational, verbal/emotional, and threat) and offline dating violence victimization-related factors (i.e., physical and psychological); and small relationships with other risk factors (i.e., sexual offline dating violence victimization, attachment styles, and jealousy), protective factors (i.e., family support and emotional regulation), and mental health symptoms (i.e., depression, anxiety, and alcohol use). There was also statistically significant and robust relationship between cyber dating violence victimization and verbal/emotional offline dating violence victimization (i.e., risk factor); medium relationships with some risk factors, including offline dating violence perpetration-related factors (i.e., psychological and verbal/emotional) and offline dating violence victimization-related factors (i.e., physical, psychological, sexual, relational, and threat); small relationships with other risk factors (i.e., physical offline dating violence perpetration, attachment styles, childhood sexual abuse), protective factors (i.e., family support, emotional regulation, and self-esteem), and mental health symptoms (i.e., depression, anxiety, stress, alcohol use, and drug use). The study's results highlight risk and protective factors associated with cyber dating violence and demonstrate its association with mental health symptoms.Article Citation - WoS: 1Citation - Scopus: 2Dataseton Maternal Attitudes About Child Maltreatment in Nine Countries Using a Q-Sort Methodology(Elsevier, 2020) Mels, Cindy; Alink, Lenneke; Branger, Marjolein; Carcamo, Rodrigo; Van Ginkel, Joost); Wang, Lamei; Yavuz Müren, Melis; Asanjarani, Faramarz; Soares, Isabel; Emmen, Rosanneke; Selcuk, Bilge; Hsiao, Celia; Woudstra, Mi-lan; Mesman, JudiAnalyses of the present data are reported in the article "Crossing Boundaries: A Pilot Study of Maternal Attitudes about Child Maltreatment in Nine Countries"[8]. Data were collected during home visits using the Maltreatment Q-Sort (MQS). A total of 466 mothers from nine different countries gave their opinion about child maltreatment by sorting 90 cards with parenting behaviors taken from the literature that reflect four types of child maltreatment, into 9 evenly distributed stacks (with 10 cards each) from least to most harmful for the child. This data article provides an overview of the content of the 90 items, which type of maltreatment they reflect, and the source of the items. The percentage of mothers labelling each of the MQS items as maltreatment is also presented. In addition, instructions are included about the administration of the MQS as well as data-entry and analyses of Q-sort data, accompanied by example datasets and syntaxes. This can serve as a manual for researchers interested in using Q-sort data.Article Citation - WoS: 15Citation - Scopus: 14Dating Infidelity in Turkish Couples: the Role of Attitudes and Intentions(Taylor & Francis, 2017) Fincham, Frank D; Toplu Demirtaş, EzgiStudies on dating infidelity have mostly been carried out in individualistic, Western cultures and have tended to investigate either attitudes or intentions toward infidelity in isolation from each other. The current study therefore investigated dating infidelity in a more collectivist, predominantly Muslim culture. Informed by the theory of planned behavior, it tested intentions as a potential mechanism that might account for the association between attitudes toward infidelity and reported infidelity. In doing so, the role of gender and infidelity history was also investigated in regard to attitudes and intentions toward infidelity. A sample of 420 college students (292 women) completed the Turkish versions of the Attitudes Towards Infidelity Scale and the Intentions Towards Infidelity Scale. A 2 (gender) × 2 (infidelity history: yes, no) multivariate analysis of variance (MANOVA) revealed main effects but no interaction effect. Men compared to women and cheaters compared to noncheaters reported more favorable attitudes and intentions toward infidelity. Moreover, intentions toward infidelity fully and partly mediated the association between attitudes toward infidelity and infidelity for women and men, respectively. Findings are interpreted in light of dating infidelity research, with a focus on universal and culturally specific aspects. Recommendations are made for future research.Article Determining the Effect of Video Information on the Dental Anxiety Levels of the Endodontic Patients: a Randomised Clinical Trial(Wiley, 2025) Anatürk, Şule; Dönmez Özkan, Hicran; Saral, İlkim Pınar; Çakar, TunaObjective The present study assessed the effectiveness of pretreatment education in the form of Visual Video Information (VVI) on the anxiety levels of patients during endodontic treatment steps. Methods Patients (n = 120) having single-rooted teeth with a single root canal diagnosed with asymptomatic irreversible pulpitis and/or pre-prosthetic root canal treatment were included in this study. After completing anxiety scales and a sociodemographic/dental habits survey, the patients were randomly divided into two groups. Just before the endodontic treatment, VVI was given to the video group patients, while the control group patients received routine information verbally. In both groups, a galvanic skin response (GSR) device was placed on the patients' wrists to record the stress levels during the endodontic treatment process. Anxiety scales and a feedback-satisfaction survey were administered to all patients after the treatment process. Then, statistical analysis was performed (alpha = 0.05). Results This study performed 60 endodontic treatments on 60 patients (30 females and 30 males). Sociodemographic characteristics and dental treatment habits of the patients significantly affected dental anxiety scale scores (p < 0.05). VVI resulted in a significant decrease in the mean scores of anxiety before and after the treatment, but this decrease was not significant between the groups (p > 0.05). Similarly, VVI did not impact the GSR readings between the groups during treatment (p > 0.05). Conclusions The educational VVI is effective for reducing anxiety in patients undergoing endodontic treatment. In addition, the electrodermal activity method is a promising alternative for objectively assessing anxiety levels.Article Citation - WoS: 1Citation - Scopus: 1Developmental Differences in Children and Adults' Enforcement of Explore Versus Exploit Search Strategies in the United States and Turkey(Wiley, 2024) Kiefer, Sarah L.; Aksu, Ece; Şen, Hilal H.; Lucca, KelseyAcross development, as children acquire a deeper understanding of their environment, they explore less and take advantage, or "exploit," what they already know. Here, we test whether children also enforce exploration-oriented search behaviors onto others. Specifically, we ask whether children are more likely to encourage a search agent to explore versus exploit their environment, and whether this pattern varies across childhood (between 3 and 6 years). We also ask whether this pattern differs between children and adults, and generalizes across two different sociocultural contexts-Turkey and the United States-that differ on dimensions that might relate to children's decisions about exploration (e.g., curiosity-focused educational practices, attitudes toward uncertainty avoidance). Participants (N = 358) watched an agent search for rewards and were asked at various points whether the agent should "stay" (exploit) in their current location, or "go" (explore) to a new location. At all points in the experiment, children enforced exploration significantly more often than adults. Early in the agent's search, children in the US enforced exploration more often than children in Turkey; later in the search, younger children (from both sociocultural contexts) were more likely to continue enforcing exploration compared to older children. These findings highlight that children are not only highly exploratory themselves, but also enforce exploration onto others-underscoring the central role that exploration plays in driving early cognitive development across diverse sociocultural contexts.Research Highlights The current study examined developmental and cross-cultural differences in children and adults' enforcement of explore-exploit search strategies. Children in the US and Turkey enforced exploration more than adults, who enforced exploitation more often; results were generally consistent across cultures with small differences. Mirroring developmental changes in children's own search behavior; the tendency to enforce exploration decreased between 3- to 6-years of age. Findings underscore the central role of an "exploration mindset" in children's early decision-making-even when exploration has no direct benefits to the child themselves.Article Citation - WoS: 10Citation - Scopus: 13Displacement of a Bubble by Acoustic Radiation Force Into a Fluid-Tissue Interface(2018) Körük, Hasan; Choi, James JMicrobubbles in an ultrasound beam experience a primary Bjerknes force, which pushes the microbubbles against a fluid-tissue interface and deforms the tissue. This interaction has been used to measure tissue elasticity and is a common interaction in many therapeutic and diagnostic applications, but the mechanisms of deformation, and how the deformation dynamic depends on the bubble and ultrasound parameters, remain unknown. In this study, a mathematical model is proposed for the displacement of a bubble onto a fluid-tissue interface and the tissue deformation in response to the primary Bjerknes force. First, a model was derived for static loading and the model's prediction of bubble-mediated tissue displacement and stresses in tissue were explored. Second, the model was updated for dynamic loading. The results showed that the bubble is both displaced by the applied force and changes its shape. The bubble displacement changes nonlinearly with the applied force. The stress values in tissue are quite high for a distance within one radius of the bubble from the bubble surface. The model proposed here is permissible in human tissue and can be used for biomedical ultrasound applications, including material characterization. (C) 2018 Acoustical Society of America.Article Citation - WoS: 29Citation - Scopus: 26Drivers of Cultural Success: the Case of Sensory Metaphors(2015) Berger, Jonah; Akpınar, EzgiWhy do some cultural items catch on and become more popular than others? Language is one of the basic foundations of culture. But what leads some phrases to become more culturally successful? There are multiple ways to convey the same thing and phrases with similar meanings often act as substitutes, competing for usage. A not so friendly person, for example, can be described as unfriendly or cold. We study how the senses shape cultural success, suggesting that compared with their semantic equivalents (e.g., unfriendly person), phrases which relate to senses in metaphoric ways (e.g., cold person) should be more culturally successful. Data from 5 million books over 200 years support this prediction: Sensory metaphors are used more frequently over time than are their semantic equivalents. Experimental evidence demonstrates that sensory metaphors are more memorable because they relate more to the senses and have more associative cues. These findings shed light on how senses shape language and the psychological foundations of culture more broadly.Article Citation - WoS: 13Citation - Scopus: 14Economic Outcomes in Patients With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer Treated With Enzalutamide or Abiraterone Acetate Plus Prednisone(Springer, 2020) Lechpammer, Stanislav; Ramaswamy, Krishnan; Wang, Li; Mardekian, Jack; George, Daniel J.; Sandin, Rickard; Schultz, Neil M.; Başer, Onur; Huang, AhongIntroduction: Prostate cancer (PC) is the second leading cause of cancer death among US men and accounts for considerable healthcare expenditures. We evaluated economic outcomes in men with chemotherapy-naı¨ve metastatic castration-resistant PC (mCRPC) treated with enzalutamide or abiraterone acetate plus prednisone (abiraterone). Methods: We performed a retrospective analysis on 3174 men (18 years or older) utilizing the Veterans Health Administration (VHA) database from 1 April 2014 to 31 March 2018. Men with mCRPC were included if they had at least one pharmacy claim for enzalutamide or abiraterone (first claim date = index date) following surgical or medical castration, had no chemotherapy treatment within 12 months prior to the index date, and had continuous VHA enrollment for at least 12 months pre- and post-index date. Men were followed until death, disenrollment, or end of study and were 1:1 propensity score matched (PSM). All-cause and PC-related resource use and costs per patient per month (PPPM) in the 12 months post index were compared between matched cohorts. Results: We identified 1229 men with mCRPC prescribed enzalutamide and 1945 prescribed abiraterone with mean ages of 74 and 73 years, respectively. After PSM, each cohort had 1160 patients. The enzalutamide cohort had fewer all-cause (2.51 vs 2.86; p\0.0001) and PC-related outpatient visits (0.86 vs 1.03; p\0.0001), with corresponding lower all-cause ($2588 vs $3115; p\0.0001) and PC-related ($1356 vs $1775; p\0.0001) PPPM outpatient costs compared with the abiraterone cohort. Allcause total costs (medical and pharmacy) PPPM ($8085 vs $9092; p = 0.0002) and PC-related total costs PPPM ($6321 vs $7280; p\0.0001) were significantly lower in the enzalutamide cohort compared with the abiraterone cohort. Conclusions: Enzalutamide-treated men with chemotherapy-naı ¨ve mCRPC had significantly lower resource utilization and healthcare costs compared with abiraterone-treated men. Plain Language Summary: Plain language summary available for this article.
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